المواصفات

PROPERTIES:
Fexofenadine is the active carboxylic acid metabolite of Terfenadine. It is non-sedating selective histamine H1 receptor antagonist. Fexofenadine exhibits an anti histaminic effect beginning within 1 hour, reaching the maximum effect at 6 hours and lasting for 24 hours. It is rapidly absorbed from the GI-tract into the body oral administration with tmax occurring at approx 1-3 hours after dose. Peak plasma concentration is achieved in about 2-6 hours, it is 60-70% plasma protein bound. Its major route of elimination is via biliary excretion, while up to 10% of the ingested dose is excreted unchanged through the urine.

INDICATIONS:
Fexotel is used for symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria.